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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN3
All Species:
30.3
Human Site:
Y585
Identified Species:
47.62
UniProt:
Q6P5Z2
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P5Z2
NP_037487.2
889
99421
Y585
F
K
G
T
G
K
Y
Y
A
I
K
A
L
K
K
Chimpanzee
Pan troglodytes
XP_001159776
886
99121
Y582
F
K
G
T
G
K
Y
Y
A
I
K
A
L
K
K
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
Y698
F
K
G
T
G
K
Y
Y
A
I
K
A
L
K
K
Dog
Lupus familis
XP_548434
951
104664
Y647
F
K
G
T
G
K
Y
Y
A
I
K
A
L
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K045
878
97863
Y574
Y
K
G
T
G
K
Y
Y
A
I
K
A
L
K
K
Rat
Rattus norvegicus
O08874
985
112050
F684
Y
K
H
T
N
E
M
F
A
I
K
A
L
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
Y689
A
K
G
T
G
R
H
Y
A
I
K
A
L
K
K
Chicken
Gallus gallus
XP_422357
1013
114806
F712
Y
K
N
T
N
E
M
F
A
I
K
A
L
K
K
Frog
Xenopus laevis
Q7ZX15
486
56292
A237
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
Zebra Danio
Brachydanio rerio
XP_697542
940
106140
Y640
F
K
R
T
G
K
L
Y
A
I
K
A
L
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
N385
F
F
V
M
E
Y
V
N
G
G
D
L
M
F
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
T448
A
L
H
S
S
F
Q
T
S
D
R
L
F
F
V
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
F498
Y
K
T
T
G
E
F
F
A
I
K
A
L
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
C850
S
K
N
T
D
R
L
C
A
I
K
V
L
K
K
Red Bread Mold
Neurospora crassa
P87253
1142
127954
Y843
T
K
K
S
R
K
L
Y
A
I
K
V
L
K
K
Conservation
Percent
Protein Identity:
100
97.7
81.5
84.2
N.A.
83.2
49.9
N.A.
64.2
48.9
26.2
52.2
N.A.
28
N.A.
29.1
41.5
Protein Similarity:
100
97.8
82.9
87.6
N.A.
88.4
63.6
N.A.
72.9
63
36.6
67.6
N.A.
41.5
N.A.
43.9
58.2
P-Site Identity:
100
100
100
100
N.A.
93.3
60
N.A.
80
60
13.3
86.6
N.A.
6.6
N.A.
0
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
80
N.A.
93.3
80
20
86.6
N.A.
20
N.A.
20
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
27.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
43.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
60
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
0
0
0
0
7
80
0
0
67
0
0
0
% A
% Cys:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
0
0
7
7
0
0
0
0
% D
% Glu:
0
0
0
0
7
27
0
0
0
0
0
7
0
0
0
% E
% Phe:
40
7
7
0
0
7
7
20
0
0
0
0
7
20
7
% F
% Gly:
0
0
40
0
54
0
0
0
7
14
7
0
0
0
0
% G
% His:
0
0
14
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
80
0
0
0
0
0
% I
% Lys:
0
80
7
0
0
47
0
0
0
0
80
0
0
80
80
% K
% Leu:
7
7
0
0
0
0
20
0
0
0
0
14
87
0
0
% L
% Met:
0
0
0
7
7
0
14
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
14
0
14
0
0
7
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% Q
% Arg:
0
0
7
0
7
14
0
0
0
0
7
0
0
0
0
% R
% Ser:
7
0
0
14
7
0
0
0
7
0
0
0
0
0
0
% S
% Thr:
7
0
7
74
0
0
0
7
0
0
0
0
0
0
0
% T
% Val:
0
0
7
7
0
0
7
0
0
0
0
14
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
27
0
0
0
0
7
40
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _